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BMJ Open Diabetes Res Care. 2021 May; 9 (1): e002134. doi: 10.1136 / bmjdrc-2021-002134.
INTRODUCTION: Adolescents with type 2 diabetes are at increased risk for cardiovascular disease (CVD). It is unclear whether regular physical activity (PA) changes this risk.
RESEARCH DESIGN AND METHODS: We compared CVD risk factors in a cross-sectional study of 164 adolescents with type 2 diabetes stratified after high intensity weekly PA. Results were hemoglobin A1c (HbA1c), ambulatory blood pressure (BP; ambulatory 24-hour measurements), plasma lipoproteins, and albuminuria. The main exposure, high-intensity PA, was quantified using the adolescent physical activity recall questionnaire.
Results: Adolescents were 15 ± 3 years old and 78% lived in the countryside and 68% were female, with a mean body mass index (BMI) Z-score of 2.4 ± 1.1 and a mean HbA1c of 9.6% ± 2.6%. Adolescents who participated in regular PA with high intensity (40%; n = 67) achieved almost twice the PA dose than their peers who did not (62 vs. 34 metabolic equivalent score hour / week, p = 0.001). After adjusting for diabetes duration, BMI-Z-Score, gender and smoking, adolescents who dealt with PA with high intensity showed a lower HbA1c (9.1% versus 9.9%, p = 0.052) and diastolic blood pressure (70 mm Hg versus 73 mm Hg), p = 0.002), diastolic load (20% versus 26%, p = 0.023) and mean arterial pressure (87.3 mm Hg versus 90.3 mm Hg, p <0.01) im Compared to teenagers who didn't. Compared to adolescents who did not participate in regular high-intensity PA, those who also showed a lower likelihood of albuminuria after seeing duration of diabetes, gender, smoking, rural life, and BMI Z-score, showed adjusted (adjusted OR: 0.40, 95%) CI 0.19 to 0.84).
CONCLUSIONS: In adolescents with type 2 diabetes, participation in high-intensity PA is associated with a lower risk of CVD.
PMID: 33990367 | DOI: 10.1136 / bmjdrc-2021-002134