Predictors of Demise, Discharge ID’d for Diabetes Sufferers With COVID-19


TUESDAY, February 23, 2021 (HealthDay News) – About 20 percent of patients hospitalized with COVID-19 will die with diabetes within 28 days and about 50 percent will be discharged, according to a published study. Predictors for death and discharge were identified online February 17 in Diabetologia.

Matthieu Wargny, MD of the University of Nantes in France and colleagues studied patients with diabetes who were hospitalized after hospitalization for COVID-19, with an emphasis on hospital discharge and death within 28 days. Data were collected for 2,796 participants.

The researchers found that 44.2 and 38.6 percent of participants had microvascular and macrovascular diabetic complications, respectively. Within 28 days, 20.6 percent died and 50.2 percent were discharged from the hospital with a median hospital stay of nine days. Positive associations with discharge were observed for younger age, routine metformin therapy, and longer symptom duration on admission in multivariable models. Variables associated with a decreased likelihood of discharge included a history of microvascular complications, routine anticoagulant therapy, dyspnea on admission, and higher aspartate aminotransferase, white blood cell count, and C-reactive protein levels. Factors associated with death within 28 days were also associated with discharge, including routine insulin and statin treatment, which correlated with increased risk.

“Identifying beneficial variables associated with discharge from hospital and harmful variables associated with death can result in patient reclassification and help appropriately use resources according to individual patient profiles,” the authors write.

Several authors disclosed financial relationships with pharmaceutical companies, some of which funded the study.

Abstract / full text

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