THURSDAY, April 8, 2021 (HealthDay News) – According to a study published online April 6 in the European Journal of Preventive Cardiology, the prevalence of diabetes in patients with chronic coronary syndrome varies but is associated with increased mortality and cardiovascular events.
Koon-Hou Mak, MD, of the Mak Heart Clinic in Singapore, and colleagues examined the prevalence and prognostic impact of diabetes by geographic region and ethnicity in an observational registry of patients with chronic coronary syndromes in 45 countries from 2009-2010 followed annually for five years.
The researchers found that 29 percent of the 32,694 patients had diabetes, with regional prevalence in Northern Europe and the Gulf States ranging from <20 percent to ~ 60 percent. Diabetes was associated with an increased risk for the primary endpoint (cardiovascular death, myocardial infarction, or stroke) in a multivariable model (adjusted hazard ratio, 1.28) and for all secondary endpoints (overall cause and cardiovascular mortality, myocardial infarction, stroke, heart) Failure and coronary revascularization). Modest differences in results by geography and ethnicity were observed.
“Improved strategies to slow the progression of diabetes and more effective interventions to prevent its adverse consequences through lifestyle changes, revascularization procedures and pharmacological therapies are urgently needed,” the authors write.
Several authors disclosed financial ties to pharmaceutical companies, including Servier, which funded the CLARIFY registry.
Abstract / full text